Blog Posts

Challenges Faced by Tablets and Capsules: A Blog Post When it comes to the pharmaceutical industry, the development of solid dosage forms such as tablets and capsules involves intricate processes that are susceptible to various challenges. Both tablets and capsules share common hurdles that can significantly impact the production and

    Knowing how formulation moves through a tablet process is invaluable in optimizing the process for the greatest tablet quality and production. Residence time refers to the total time a particle or batch of material spends in a particular process or piece of equipment.  In tablet compression, this refers

In the world of tablet manufacturing, the phenomenon of “tablet sticking” has been a persistent challenge, often leading to production delays, quality issues, and increased costs. The science behind tablet sticking is complex, but understanding it is essential for pharmaceutical and nutraceutical companies seeking to optimize their production processes and

In the pharmaceutical industry, every capsule and tablet begins with a concept. Transforming that idea into a tangible product requires an expert manufacturing partner. Natoli stands out as a leader in pharmaceutical equipment and services, providing a comprehensive journey from formulation to full-scale production. Natoli Scientific: The Foundation of Formulation

In the dynamic realm of pharmaceuticals, Quality by Design (QbD) reigns as a transformative force. It’s more than just a concept; it’s the cornerstone of pharmaceutical excellence. Join us as we delve into the critical role that QbD plays in shaping the future of tablet development. Quality by Design (QbD)

Every capsule and tablet begins with an idea. It takes a professional and innovative manufacturing partner to turn that idea into a reality. Enter Natoli, a name synonymous with excellence in pharmaceutical equipment and services. From the early stages of formulation to the grand scale of full-blown production, Natoli offers

In the dynamic realm of pharmaceuticals, Quality by Design (QbD) reigns as a transformative force. It’s more than just a concept; it’s the cornerstone of pharmaceutical excellence. Join us as we delve into the critical role that QbD plays in shaping the future of tablet development. Quality by Design (QbD)

Understanding the fine details of powder properties is crucial in the pharmaceutical industry, where the behavior of particulate matter can affect manufacturability and the efficacy of the final product. Natoli Scientific offers advanced on-site analysis of powder Micromeritics, which encompasses particle size distribution, flowability, and compaction properties. By assessing these

Are you curious about how additives can influence the electrostatic charge build-up of excipients in pharmaceutical manufacturing? Join us on a journey to uncover the hidden dynamics of powder flow and electrostatic charge accumulation, a crucial aspect of powder processing that can significantly affect the quality and efficiency of pharmaceutical

Compaction Simulation / Emulation Building on the capabilities of the NP-RD10A benchtop tablet press (discussed in our previous article on USP <1062>), our services are further enhanced by the integration of the Presster™ compaction emulator. This state-of-the-art tool is designed to replicate the compaction dynamics of production tablet presses in

Batch/Lot Testing for Release Batch and lot testing for release are critical steps in ensuring the quality and consistency of pharmaceutical tablets. Natoli Scientific provides comprehensive batch testing services that align with stringent industry standards and regulatory requirements. Each lot undergoes a rigorous analysis to verify that it meets predefined

In pharmaceutical testing, the development and validation of analytical methods are absolute musts when it comes to reliable quality control. Natoli Scientific is at the forefront of offering comprehensive analytical method development and validation services designed to ensure the integrity of your company’s drug formulations. Our expert team develops robust

Natoli Scientific takes pride in its comprehensive USP<1062> Tablet Compression Characterization services, tailored to address the complexities of tableting in pharmaceutical manufacturing. Staying true to the parameters outlined in the United States Pharmacopeia (USP) Chapter 1062, our approach meticulously evaluates tablet compression behaviors. By thoroughly characterizing the compression profile, we

Natoli Scientific’s preclinical stability studies represent a critical facet of our pharmaceutical testing services, providing essential data on the shelf life and storage conditions of drug candidates. These studies are expertly designed to evaluate physical, chemical, and microbiological stability, ensuring that formulations retain their safety, efficacy, and quality over time.